
我的研究領域為分子生態與演化、魚類基因體與奈米孔定序應用。近期研究著重在微生物功能基因演化與應用、淡水魚類的親緣地理學、魚類雜交行為與基因體研究。我主要協助 (a)共儀設施管理和相關培訓課程,(b)生物安全和動物實驗相關事宜,(c)新建實驗室規劃。
我參與完成的研究項目有
- 酵母順式和反式調節基因表現的天擇
- 利用多體學分析鑑定微生物纖維素酶功能
- 酵母中有氧醱酵的演化
- 魚類視蛋白基因演化
- 微生物酶對三萜類化合物的生物轉化
- 魚類基因體學和種間交配行為
期刊論文
- Wu JY, Ding HY, Wang TY, Cai CZ, Chang TS*, 2022, “Application of Biotransformation-Guided Purification in Chinese Medicine: An Example to Produce Butin from Licorice”, Catalysts, 12(7), 718. (SCIE) (IF: 3.52; SCI ranking: 40.9%)
- Ding HY, Wang TY, Wu JY, Tsai YL, Chang TS*, 2022, “Enzymatic Synthesis of Novel and Highly Soluble Puerarin Glucoside by Deinococcus geothermalis Amylosucrase”, Molecules, 27(13), 4074. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
- De Vivo M, Lee HH, Huang YS, Dreyer N, Fong CL, de Mattos FMG, Jain D, Wen YHV, Mwihaki JK, Wang TY, Machida RJ, Wang J, Chan BKK, Tsai IJ*, 2022, “Utilisation of Oxford Nanopore sequencing to generate six complete gastropod mitochondrial genomes as part of a biodiversity curriculum”, Scientific Reports, 12(9973), 1-11. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
- Wu JY, Ding HY, Luo SY, Wang TY, Tsai YL, Chang TS*, 2022, “Novel Glycosylation by Amylosucrase to Produce Glycoside Anomers”, Biology-Basel, 11(6), 822.
- Wang PH*, Chen YL, Wu TY, Wu YW, Wang TY, Shih CJ, Wei STS, Lai YL, Liu CX, Chiang YR*, 2022, “Omics and mechanistic insights into di-(2-ethylhexyl) phthalate degradation in the O2-fluctuating estuarine sediments”, Chemosphere, 299, 134406. (SCIE) (IF: 5.778; SCI ranking: 10.9%)
- Goh KS, Lee CM, Wang TY*, 2022, “Species-Specific Flash Patterns Track the Nocturnal Behavior of Sympatric Taiwanese Fireflies”, Biology-Basel, 11(1), 58. (SCIE) (IF: 3.796; SCI ranking: 20.4%)
- Wu JY, Ding HY, Wang TY, Tsai YL, Ting HJ, Chang TS*, 2021, “Improving Aqueous Solubility of Natural Antioxidant Mangiferin through Glycosylation by Maltogenic Amylase from Parageobacillus galactosidasius DSM 18751”, Antioxidants, 10(11), 1817. (SCIE) (IF: 5.014; SCI ranking: 11.5%,18.9%,7.2%)
- Chiang CM, Wang TY, Wu JY, Zhang YR, Lin SY, Chang TS*, 2021, “Production of New Isoflavone Diglucosides from Glycosylation of 8-Hydroxydaidzein by Deinococcus geothermalis Amylosucrase”, Fermentation, 7(4), 232. (SCIE) (IF: ; )
- Wu JY, Wang TY, Ding HY, Zhang YR, Lin SY, Chang TS*, 2021, “Enzymatic Synthesis of Novel Vitexin Glucosides”, Molecules, 26, 6274. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
- Gómez-Luciano LB, Wu YW, Chiang CM, Chang TS, Wu JY*, Wang TY*, 2021, “Complete Genome Sequence of the Soil-Isolated Psychrobacillus sp. Strain AK 1817, Capable of Biotransforming the Ergostane Triterpenoid Antcin K”, Microbiology Resource Announcements, 10(40), e01242-20. (SCIE) (IF: ; )
- Wu JY, Ding HY, Wang TY, Zhang YR, Chang TS*, 2021, “Glycosylation of Ganoderic Acid G by Bacillus Glycosyltransferases”, International Journal of Molecular Sciences, 22(18), 9744. (SCIE) (IF: 4.556; SCI ranking: 27.1%,24.9%)
- Wang LJ, Wu YW, Wang TY*, 2021, “Characterization of the complete mitochondrial genome of Abscondita cerata (Olivier, 1911) (Coleoptera: Lampyridae) and its phylogenetic implications”, MITOCHONDRIAL DNA PART B-RESOURCES, 6(9), 2528-2530. (SCIE) (IF: 0.885; SCI ranking: 93.8%)
- Chang TS*, Chiang CM, Wang TY, Tsai YL, Wu YW, Ting HJ*, Wu JY*, 2021, “One-Pot Bi-Enzymatic Cascade Synthesis of Novel Ganoderma Triterpenoid Saponins”, Catalysts, 11(5), 580. (SCIE) (IF: 3.52; SCI ranking: 40.9%)
- Chang TS, Wang TY, Chiang CM, Lin YJ, Chen HL, Wu YW, Ting HJ*, Wu JY, 2021, “Biotransformation of celastrol to a novel, well-soluble, low-toxic and anti-oxidative celastrol-29-O-β-glucoside by Bacillus glycosyltransferases”, Journal of Bioscience and Bioengineering, 131(2), 176-182. (SCIE) (IF: 2.366; SCI ranking: 54.5%,41.7%)
- Liao NL, Huang SP, Wang TY*, 2020, “Interspecific mating behavior between introduced Zacco platypus and native Opsariichthys evolans in Taiwan”, Zoological Studies, 59, e6. (SCIE) (IF: 1.257; SCI ranking: 46.2%)
- Mullis A, Lu Z, Zhan Y, Wang TY, Rodriguez J, Rajeh A, Chatrath A, Lin Z*, 2020, “Parallel concerted evolution of ribosomal protein genes in fungi and its adaptive significance”, Molecular Biology and Evolution, 37(2), 455-468. (SCIE) (IF: 11.062; SCI ranking: 6.1%,7.8%,3.9%)
- Chang TS, Wang TY, Hsueh TY, Lee YW, Wu JY, Chiang CM, Chuang HM, Cai WX, Wu YW*, 2019, “A genome-centric approach reveals a novel glycosyltransferase from the GA A07 strain of Bacillus thuringiensis responsible for catalyzing 15-O-Glycosylation of ganoderic acid A”, International Journal of Molecular Sciences, 20(20), 5192. (SCIE) (IF: 4.556; SCI ranking: 27.1%,24.9%)
- Chang TS, Chiang CM, Kao YH, Wu JY, Wu YW, Wang TY*, 2019, “A new triterpenoid glucoside from a novel acidic glycosylation of ganoderic acid A via recombinant glycosyltransferase of Bacillus subtilis”, Molecules, 24(19), 3457. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
- Chang TS, Wang TY, Yang SY, Kao YH, Wu JY*, Chiang CM*, 2019, “Potential industrial production of a well-soluble, alkaline-stable, and anti-inflammatory isoflavone glucoside from 8-hydroxydaidzein glucosylated by recombinant amylosucrase of Deinococcus geothermalis”, Molecules, 24(12), 2236. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
- Chang TS, Ko HH, Wang TY, Lee CH, Wu JY*, 2018, “Biotransformation of ganoderic acid A to 3-O-acetyl ganoderic acid A by soil-isolated Streptomyces sp.”, Fermentation, 4(4), 101.
- Chang TS, Wu JY, Wang TY, Wu KY, Chiang CM*, 2018, “Uridine Diphosphate-Dependent Glycosyltransferases from Bacillus subtilis ATCC 6633 Catalyze the 15-O-Glycosylation of Ganoderic Acid A”, International Journal of Molecular Sciences, 19(11), 3469. (SCIE) (IF: 4.556; SCI ranking: 27.1%,24.9%)
- Tseng WH, Lin JW, Lou CH, Lee KH, Wu LS, Wang TY, Wang FY*, Irschick DJ, Lin SM*, 2018, “Opsin gene expression regulated by testosterone level in a sexually dimorphic lizard”, Scientific Reports, 8, 16055. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
- Chang TS, Chiang CM, Wang TY, Lee CH, Lee YW, Wu JY*, 2018, “New triterpenoid from novel triterpenoid 15-O-glycosylation on ganoderic acid A by intestinal bacteria of zebrafish”, Molecules, 23(9), 2345. (SCIE) (IF: 3.267; SCI ranking: 47.8%,39.5%)
- Chiang CM, Wang TY, Yang SY, Wu JY*, Chang TS*, 2018, “Production of new isoflavone glucosides from glycosylation of 8-hydroxydaidzein by glycosyltransferase from Bacillus subtilis ATCC 6633”, Catalysts, 8(9), 387. (SCIE) (IF: 3.52; SCI ranking: 40.9%)
- Lee MH, Lin JJ, Lin YJ, Chang JJ, Ke HM, Fan WL, Wang TY, Li WH*, 2018, “Genome-wide prediction of CRISPR/Cas9 targets in Kluyveromyces marxianus and its application to obtain a stable haploid strain”, Scientific Reports, 8(1), 7305. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
- Huang SP, Wang FY, Wang TY*, 2017, “Molecular phylogeny of the Opsariichthys group (Teleostei: Cypriniformes) based on complete mitochondrial genomes”, Zoological Studies, 56, 40. (SCIE) (IF: 1.257; SCI ranking: 46.2%)
- Lin JJ, Wang FY, Li WH*, Wang TY*, 2017, “The rises and falls of opsin genes in 59 ray-finned fish genomes and their implications for environmental adaptation”, Scientific Reports, 7(1), 15568. (SCIE) (IF: 3.998; SCI ranking: 23.9%)
- Chiang CM, Wang TY, Ke AN, Chang TS*, Wu JY*, 2017, “Biotransformation of ergostane triterpenoid antcin K from Antrodia cinnamomea by soil-isolated Psychrobacillus sp. AK 1817”, Catalysts, 7(10), 299. (SCIE) (IF: 3.52; SCI ranking: 40.9%)
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gate.sinica.edu.tw

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