我的研究領域為分子生態與演化、魚類基因體與奈米孔定序應用。近期研究著重在微生物功能基因演化與應用、淡水魚類的親緣地理學、魚類雜交行為與基因體研究。我主要協助 (a)共儀設施管理和相關培訓課程，（b）生物安全和動物實驗相關事宜，（c）新建實驗室規劃。
我參與完成的研究項目有

1. 酵母順式和反式調節基因表現的天擇
2. 利用多體學分析鑑定微生物纖維素酶功能
3. 酵母中有氧醱酵的演化
4. 魚類視蛋白基因演化
5. 微生物酶對三萜類化合物的生物轉化
6. 魚類基因體學和種間交配行為

期刊論文

1. Wu JY, Ding HY, Wang TY, Cai CZ, Chang TS*, 2023, “Antioxidant and anti-α-glucosidase activities of biotransformable dragon’s blood via predicted data mining approach”, Process Biochemistry, 130, 166-173. (SCIE) (IF: 3.757; SCI ranking: 52.2%,40%,35.7%)
2. Wang TY, Goh KS, Wang LJ, Wu LL, Wang FY*, Wu YW*, 2023, “Long-Read Genome Sequencing of Abscondita cerata (Coleoptera: Lampyridae), the Endemic Firefly of Taiwan”, Zoological Studies, 62, 25. (SCIE) (IF: 2.058; SCI ranking: 30.3%)
3. Dreyer N*, de Mattos FMG*, Jain D*, Fong CL, De Vivo M, Wen YV, Huang YS, Mwihaki JK, Lee HH, Tsai PC, Tsao YF, Chan BKK, Tsai IJ, Machida RJ, Wang TY, Wang J, 2023, “The mitochondrial genome of Isognomon nucleus and mitogenomics of Pteriomorphia (Mollusca: Bivalvia: Autobranchia)”, Journal of Molluscan Studies, 89(1), eyad003. (SCIE) (IF: 1.348; SCI ranking: 68.5%,56%)
4. Ding HY, Wang TY, Wu JY, Zhang YR, Chang TS*, 2023, “Novel Ganoderma triterpenoid saponins from the biotransformation-guided purification of a commercial Ganoderma extract”, Journal of Bioscience and Bioengineering, 135(5), 402-410. (SCIE) (IF: 2.894; SCI ranking: 56.9%,46.5%)
5. Goh KS, Wang LJ, Ni JH, Wang TY*, 2022, “Luminescent characteristics and mitochondrial COI barcodes of nine cohabitated Taiwanese fireflies”, PeerJ, 10, e14195. (SCIE) (IF: 2.984; SCI ranking: 37%)
6. Morgan B, Wang TY, Chen YZ, Moctezuma V, Burgos O, Le MH, Huang JP*, 2022, “Long-read sequencing data reveals dynamic evolution of mitochondrial genome size and the phylogenetic utility of mitochondrial DNA in Hercules beetles (Dynastes; Scarabaeidae)”, Genome Biology and Evolution, 14(10), evac147. (SCIE) (IF: 3.416; SCI ranking: 40%,47.2%)
7. Wang YL, Lin CY, Huang SP, Lee CY, Tuanmu MN*, Wang TY*, 2022, “Chub movement is attracted by the collision sounds associated with spawning activities”, Zootaxa, 5189 (1), 308-317. (SCIE) (IF: 1.091; SCI ranking: 68%)
8. Huang SP*, Wang TY, Lin TY, Huang HC, 2022, “Genetic diversity of the regionally endangered Chinese ricefish (Oryzias sinensis) in Taiwan, with comments on its conservation status”, Zootaxa, 5189 (1), 283-307. (SCIE) (IF: 1.091; SCI ranking: 68%)
9. Wu JY, Ding HY, Wang TY, Cai CZ, Chang TS*, 2022, “Application of biotransformation-guided purification in Chinese medicine: an example to produce butin from licorice”, Catalysts, 12(7), 718. (SCIE) (IF: 4.146; SCI ranking: 41.4%)
10. Ding HY, Wang TY, Wu JY, Tsai YL, Chang TS*, 2022, “Enzymatic synthesis of novel and highly soluble puerarin glucoside by Deinococcus geothermalis Amylosucrase”, Molecules, 27(13), 4074. (SCIE) (IF: 4.412; SCI ranking: 38.7%,35.2%)
11. De Vivo M, Lee HH, Huang YS, Dreyer N, Fong CL, de Mattos FMG, Jain D, Wen YHV, Mwihaki JK, Wang TY, Machida RJ, Wang J, Chan BKK, Tsai IJ*, 2022, “Utilisation of Oxford nanopore sequencing to generate six complete gastropod mitochondrial genomes as part of a biodiversity curriculum”, Scientific Reports, 12(9973), 1-11. (SCIE) (IF: 4.38; SCI ranking: 23.3%)
12. Wu JY, Ding HY, Luo SY, Wang TY, Tsai YL, Chang TS*, 2022, “Novel glycosylation by amylosucrase to produce glycoside anomers”, Biology-Basel, 11(6), 822. (SCIE) (IF: 5.079; SCI ranking: 17.2%)
13. Wang PH*, Chen YL, Wu TY, Wu YW, Wang TY, Shih CJ, Wei STS, Lai YL, Liu CX, Chiang YR*, 2022, “Omics and mechanistic insights into di-(2-ethylhexyl) phthalate degradation in the O2-fluctuating estuarine sediments”, Chemosphere, 299, 134406. (SCIE) (IF: 7.086; SCI ranking: 10.9%)
14. Goh KS, Lee CM, Wang TY*, 2022, “Species-specific flash patterns track the nocturnal behavior of sympatric Taiwanese fireflies”, Biology-Basel, 11(1), 58. (SCIE) (IF: 5.079; SCI ranking: 17.2%)
15. Wu JY, Ding HY, Wang TY, Tsai YL, Ting HJ, Chang TS*, 2021, “Improving aqueous solubility of natural antioxidant mangiferin through glycosylation by maltogenic amylase from Parageobacillus galactosidasius DSM 18751”, Antioxidants, 10(11), 1817. (SCIE) (IF: 6.313; SCI ranking: 20.2%,9.5%,7.6%)
16. Chiang CM, Wang TY, Wu JY, Zhang YR, Lin SY, Chang TS*, 2021, “Production of new isoflavone diglucosides from glycosylation of 8-hydroxydaidzein by Deinococcus geothermalis amylosucrase”, Fermentation, 7(4), 232.
17. Wu JY, Wang TY, Ding HY, Zhang YR, Lin SY, Chang TS*, 2021, “Enzymatic synthesis of novel vitexin glucosides”, Molecules, 26, 6274. (SCIE) (IF: 4.412; SCI ranking: 38.7%,35.2%)
18. Gómez-Luciano LB, Wu YW, Chiang CM, Chang TS, Wu JY*, Wang TY*, 2021, “Complete genome sequence of the soil-isolated Psychrobacillus sp. strain AK 1817, capable of biotransforming the ergostane triterpenoid antcin K”, Microbiology Resource Announcements, 10(40), e01242-20.
19. Wu JY, Ding HY, Wang TY, Zhang YR, Chang TS*, 2021, “Glycosylation of ganoderic acid G by Bacillus glycosyltransferases”, International Journal of Molecular Sciences, 22(18), 9744. (SCIE) (IF: 5.924; SCI ranking: 22.6%,27.4%)
20. Wang LJ, Wu YW, Wang TY*, 2021, “Characterization of the complete mitochondrial genome of Abscondita cerata (Olivier, 1911) (Coleoptera: Lampyridae) and its phylogenetic implications”, MITOCHONDRIAL DNA PART B-RESOURCES, 6(9), 2528-2530. (SCIE) (IF: 0.658; SCI ranking: 96.6%)
21. Chang TS*, Chiang CM, Wang TY, Tsai YL, Wu YW, Ting HJ*, Wu JY*, 2021, “One-pot bi-enzymatic cascade synthesis of novel Ganoderma triterpenoid saponins”, Catalysts, 11(5), 580. (SCIE) (IF: 4.146; SCI ranking: 41.4%)
22. Chang TS, Wang TY, Chiang CM, Lin YJ, Chen HL, Wu YW, Ting HJ*, Wu JY, 2021, “Biotransformation of celastrol to a novel, well-soluble, low-toxic and anti-oxidative celastrol-29-O-β-glucoside by Bacillus glycosyltransferases”, Journal of Bioscience and Bioengineering, 131(2), 176-182. (SCIE) (IF: 2.894; SCI ranking: 56.9%,46.5%)
23. Liao NL, Huang SP, Wang TY*, 2020, “Interspecific mating behavior between introduced Zacco platypus and native Opsariichthys evolans in Taiwan”, Zoological Studies, 59, e6. (SCIE) (IF: 2.058; SCI ranking: 30.3%)
24. Mullis A, Lu Z, Zhan Y, Wang TY, Rodriguez J, Rajeh A, Chatrath A, Lin Z*, 2020, “Parallel concerted evolution of ribosomal protein genes in fungi and its adaptive significance”, Molecular Biology and Evolution, 37(2), 455-468. (SCIE) (IF: 16.24; SCI ranking: 3%,4%,2.8%)
25. Chang TS, Wang TY, Hsueh TY, Lee YW, Wu JY, Chiang CM, Chuang HM, Cai WX, Wu YW*, 2019, “A genome-centric approach reveals a novel glycosyltransferase from the GA A07 strain of Bacillus thuringiensis responsible for catalyzing 15-O-Glycosylation of ganoderic acid A”, International Journal of Molecular Sciences, 20(20), 5192. (SCIE) (IF: 5.924; SCI ranking: 22.6%,27.4%)
26. Chang TS, Chiang CM, Kao YH, Wu JY, Wu YW, Wang TY*, 2019, “A new triterpenoid glucoside from a novel acidic glycosylation of ganoderic acid A via recombinant glycosyltransferase of Bacillus subtilis”, Molecules, 24(19), 3457. (SCIE) (IF: 4.412; SCI ranking: 38.7%,35.2%)
27. Chang TS, Wang TY, Yang SY, Kao YH, Wu JY*, Chiang CM*, 2019, “Potential industrial production of a well-soluble, alkaline-stable, and anti-inflammatory isoflavone glucoside from 8-hydroxydaidzein glucosylated by recombinant amylosucrase of Deinococcus geothermalis”, Molecules, 24(12), 2236. (SCIE) (IF: 4.412; SCI ranking: 38.7%,35.2%)
28. Chang TS, Ko HH, Wang TY, Lee CH, Wu JY*, 2018, “Biotransformation of ganoderic acid A to 3-O-acetyl ganoderic acid A by soil-isolated Streptomyces sp.”, Fermentation, 4(4), 101.
29. Chang TS, Wu JY, Wang TY, Wu KY, Chiang CM*, 2018, “Uridine Diphosphate-Dependent Glycosyltransferases from Bacillus subtilis ATCC 6633 Catalyze the 15-O-glycosylation of Ganoderic Acid A”, International Journal of Molecular Sciences, 19(11), 3469. (SCIE) (IF: 5.924; SCI ranking: 22.6%,27.4%)
30. Tseng WH, Lin JW, Lou CH, Lee KH, Wu LS, Wang TY, Wang FY*, Irschick DJ, Lin SM*, 2018, “Opsin gene expression regulated by testosterone level in a sexually dimorphic lizard”, Scientific Reports, 8, 16055. (SCIE) (IF: 4.38; SCI ranking: 23.3%)
31. Chang TS, Chiang CM, Wang TY, Lee CH, Lee YW, Wu JY*, 2018, “New triterpenoid from novel triterpenoid 15-O-glycosylation on ganoderic acid A by intestinal bacteria of zebrafish”, Molecules, 23(9), 2345. (SCIE) (IF: 4.412; SCI ranking: 38.7%,35.2%)
32. Chiang CM, Wang TY, Yang SY, Wu JY*, Chang TS*, 2018, “Production of new isoflavone glucosides from glycosylation of 8-hydroxydaidzein by glycosyltransferase from Bacillus subtilis ATCC 6633”, Catalysts, 8(9), 387. (SCIE) (IF: 4.146; SCI ranking: 41.4%)
33. Lee MH, Lin JJ, Lin YJ, Chang JJ, Ke HM, Fan WL, Wang TY, Li WH*, 2018, “Genome-wide prediction of CRISPR/Cas9 targets in Kluyveromyces marxianus and its application to obtain a stable haploid strain”, Scientific Reports, 8(1), 7305. (SCIE) (IF: 4.38; SCI ranking: 23.3%)