厭氧及極端微生物、微生物代謝多樣性、微生物之生理生態研究、環境體學分析

我的主要研究興趣是微生物代謝多樣性。目前著重於極端微生物的生理與代謝研究。極端微生物是偏好在極端環境中生長繁殖的一群微生物，通常爲單細胞原核或真核生物。極端環境係指不適合脊椎動物生活之環境，包括缺乏氧氣、極端溫度、極端酸鹼值或是高鹽度等特殊理化條件。伴隨新興微生物分析技術之興起，極端微生物之親緣及代謝多樣性研究，近來獲得許多重大進展。相關之微生物乃至酵素或代謝物，具有相當之生醫、農業與工業應用潛力。

期刊論文

1. 1.Wang PH, Chen YL, Wu TY, Wu YW, Wang TY, Shih CJ, Wei STS, Lai YL, Liu CX, Yu CP, *Chiang YR, 2022, “Omics and mechanistic insights into di-(2-ethylhexyl) phthalate degradation in the O2-fluctuating estuarine sediments.”, CHEMOSPHERE, 299, 134406. (SCIE) (IF: 7.086; SCI ranking: 10.9%)
2. Tsun-Hsien Hsiao, Tzong-Huei Lee, Meng-Rong Chuang, Po-Hsiang Wang, Menghsiao Meng, Masae Horinouchi, Toshiaki Hayashi, Yi-Lung Chen, and Yin-Ru Chiang*, 2022, “Identification of essential β-oxidation genes and corresponding metabolites for estrogen degradation by actinobacteria.”, MICROBIAL BIOTECHNOLOGY, 15, 949-966. (SCIE) (IF: 5.813; SCI ranking: 13.8%,18.2%)
3. 4.Chang CW, Miki T, Ye H, Souissi S, Adrian R, Anneville O, Be'eri-Shlevin Y, Chiang YR, Feuchtmayr H, Ichise S, Kagami M, *Hsieh CH 2022, accepted, “Causal networks of phytoplankton diversity and production are modulated by environmental context.”, NATURE COMMUNICATIONS, 13, 1140. (SCIE) (IF: 14.919; SCI ranking: 5.5%)
4. 5.AlDhafiri S, Chiang YR, EL Nayal AM, Abed RMM, Abotalib N, *Wael Ismail, accepted, “Temporal Compositional Shifts in an Activated Sludge Microbiome during Estrone Biodegradation.”, Environmental Science and Pollution Research. (SCIE) (IF: 4.223; SCI ranking: 33.2%)
5. Sean Ting-Shyang Wei, Yi-Lung Chen, Yu-Wei Wu, Tien-Yu Wu, Yi-Li Lai, Po-Hsiang Wang, Wael Ismail, Tzong-Huei Lee, and Yin-Ru Chiang*, 2021, “Integrated multi-omics investigations reveal the key role of synergistic microbial networks in removing plasticizer di-(2-ethylhexyl) phthalate from estuarine sediments.”, MSYSTEMS, 6, e00358-21. (SCIE) (IF: 6.496; SCI ranking: 15.3%)
6. Wei-Sheng Huang, Li-Ting Wang, Jwo-Sheng Chen, Yen-Ting Chen, Sean Ting-Shyang Wei, Yin-Ru Chiang, Pei-Ling Wang, Tzong-Huei Lee, Shih-Ting Lin, Lina Huang, Wung Yang Shieh*, 2021, “Vibrio nitrifigilis sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll”, ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 114, 933-945. (SCIE) (IF: 2.271; SCI ranking: 81.8%)
7. Tsun-Hsien Hsiao, Yi-Lung Chen, Menghsiao Meng, Meng-Rong Chuang, Masae Horinouchi, Toshiaki Hayashi, Po-Hsiang Wang, and Yin-Ru Chiang*, 2021, “Mechanistic and phylogenetic insights into actinobacteria-mediated estrogen biodegradation in urban estuarine sediments”, MICROBIAL BIOTECHNOLOGY, 13, 926-949. (SCIE) (IF: 5.813; SCI ranking: 13.8%,18.2%)
8. Chun-Wei Chang, Hao Ye, Takeshi Miki, Ethan R Deyle, Souissi Sami, Orlane Anneville, Rita Adrian, Yin-Ru Chiang, Satoshi Ichise, Michio Kumagai, Shin-Ichiro S Matsuzaki, Fuh-Kwo Shiah, Jiunn-Tzong Wu, Chih-Hao Hsieh, George Sugihara, 2020, “Long-term warming destabilizes aquatic ecosystems through weakening biodiversity-mediated causal networks”, GLOBAL CHANGE BIOLOGY, 26(11), 6413-6423. (SCIE) (IF: 10.863; SCI ranking: 1.7%,3%,3.3%)
9. Jih-Jung Chen, Shih-Wei Wang, Yin-Ru Chiang, Ka-Lai Pang, Yueh-Hsiung Kuo, Tsai-Yen Shih, and Tzong-Huei Lee, 2020, “Highly oxygenated constituents from a marine alga-derived fungus Aspergillus giganteus NTU967”, MARINE DRUGS, 18(6), 303. (SCIE) (IF: 5.118; SCI ranking: 19%,21.7%)
10. Po-Hsiang Wang, Yi-Lung Chen, Sean Ting-Shyang Wei, Kan Wu, Tzong-Huei Lee, Tien-Yu Wu, and Yin-Ru Chiang*, 2020, “Retroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(3), 1395-1403. (SCIE) (IF: 11.205; SCI ranking: 11%)
11. Han-Yi Fu, Shao-Lun Liu, Yin-Ru Chiang*, 2020, “Biosynthesis of ascorbic acid as a glucose-induced photoprotective process in the extremophilic red alga Galdieria partita.”, Frontiers in Microbiology, 10, 3005. (SCIE) (IF: 5.64; SCI ranking: 20.4%)
12. Yin-Ru Chiang*, Sean Ting-Shyang Wei, Po-Hsiang Wang, Pei-Hsun Wu, Chang-Ping Yu, 2019, “Microbial degradation of steroid sex hormones: Implications for environmental and ecological studies.”, MICROBIAL BIOTECHNOLOGY, DOI: 10.1111/1751-7915.13504. (SCIE) (IF: 5.813; SCI ranking: 13.8%,18.2%)
13. Kan Wu, Tzong-Huei Lee, Yi-Lung Chen, Yu-Sheng Wang, Po-Hsiang Wang, Chang-Ping Yu, Kung-Hui Chu, and Yin-Ru Chiang*, 2019, “Metabolites Involved in Aerobic Degradation of the A and B Rings of Estrogen”, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 85(3), e02223-18. (SCIE) (IF: 4.792; SCI ranking: 23.8%,31.4%)
14. Mei-Chuan Chen, Guei-Jane Wang, Yueh-Hsiung Kuo, Yin-Ru Chiang, Ting-Yu Cho, Yu-Ming Ju, Tzong-Huei Lee*, 2019, “Isoprenyl phenolic ethers from the termite nest-derived medicinal fungus Xylaria fimbriata”, JOURNAL OF FOOD AND DRUG ANALYSIS, 27(1),111-117. (SCIE) (IF: 6.079; SCI ranking: 8.3%,12.3%)
15. Sean Ting-Shyang Wei, Yu-Wei Wu, Tzong-Huei Lee, Yi-Shiang Huang, Cheng-Yu Yang, Yi-Lung Chen, and Yin-Ru Chiang*, 2018, “Microbial functional responses to cholesterol catabolism in denitrifying sludge”, mSystems, 3(5), e00113-18. (SCIE) (IF: 6.496; SCI ranking: 15.3%)
16. Min Lv, Ching Lo, Cheng-Chih Hsu, Yuwen Wang, Yin-Ru Chiang, Qian Sun, Yang Wu, Yan Li, Lingxin Chen, Chang-Ping Yu*, 2018, “Identification of enantiomeric byproducts during microalgae-mediated transformation of metoprolol by MS/MS spectrum-based networking”, FRONTIERS IN MICROBIOLOGY, 9, 2115. (SCIE) (IF: 5.64; SCI ranking: 20.4%)
17. Yi-Lung Chen, Han-Yi Fu, Tzong-Huei Lee, Chao-Jen Shih, Lina Huang, Yu-Sheng Wang, Wael Ismail, and Yin-Ru Chiang*, 2018, “Identification of estrogen degradation pathway and estrogen degraders in an activated sludge”, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 84, 84:e00001-18. (SCIE) (IF: 4.792; SCI ranking: 23.8%,31.4%)
18. Hisayoshi Nozaki1*, Noriko Ueki, Mari Takusagawa, Shota Yamashita, Osami Misumi, Ryo Matsuzaki, Masanobu Kawachi, Yin-Ru Chiang, and Jiunn-Tzong Wu, 2018, “Morphology, taxonomy and mating-type loci in natural populations of Volvox carteri in Taiwan”, BOTANICAL STUDIES, 59(1), 10. (SCIE) (IF: 2.787; SCI ranking: 34.5%)
19. Chao-Jen Shih, Yi-Lung Chen, Chia-Hsiang Wang, Sean Ting-Shyang Wei, I-Ting Lin, Wael Ahmed Ismail, and Yin-Ru Chiang*, 2017, “Biochemical mechanisms and microorganisms involved in anaerobic androgen metabolism in estuarine sediments.”, FRONTIERS IN MICROBIOLOGY, 8, 1520. (SCIE) (IF: 5.64; SCI ranking: 20.4%)
20. Yi-Lung Chen, Chang-Ping Yu, Tzong-Huei Lee, King-Siang Goh, Kung-Hui Chu, Po-Hsiang Wang, Wael Ismail, Chao-Jen Shih, and Yin-Ru Chiang*, 2017, “Biochemical Mechanisms and Catabolic Enzymes Involved in Bacterial Estrogen Degradation Pathways”, CELL CHEMICAL BIOLOGY, 24, 712-724. (SCIE) (IF: 8.116; SCI ranking: 12.8%)

專書(論文集)之一章

1. Yin-Ru Chiang* and Wael Ismail, 2017, “Chapter title: Anaerobic biodegradation of steroids”, editor(s): Timmis, Kenneth N, Volume 5: Anaerobic Utilization of Hydrocarbons, Oils and Lipids (Boll, Matthias, ed.), Handbook of Hydrocarbon and Lipid Microbiology Series, pp. 1-32, Berlin Heidelberg, Germany: Springer-Verlag.