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台灣鳥類誌 讀者回饋


3/28 15:30 Dr. Shin-Yi Lin 演講_ Genetic Dissection of TRA-1 Function and Regulation in the Sex Determination Pathways of Caenorhabditis Nematodes




李文雄院士中研院新世代基因體定序核心實驗室誠徵實驗助理1名Positions Open in High Throughput Genomics Core Facility








台灣生物多樣性資訊機構(TaiBIF)誠徵生物多樣性資訊技術員 (研發替代役可) 1名


3/28 3月份「知識饗宴」- 臺灣史研究所謝國興研究員兼所長主講「後殖民?臺灣民間信仰中的日本記憶」


3/31 3月份藝文活動「不可能的相聲」


江殷儒 助研究員


Dr. Yin-Ru Chiang

[ email ]

tel: +886-2-2787-2251

Assistant Research Fellow
PhD – University of Freiburg, Germany, 2007
Research Fields
Physiology and metabolism of bacteria, biodegradation and bioremediation, and microbial metabolomics
Major Research Achievements (2013-2017)
  • Metabolic diversity of anaerobes: Microorganisms maintain the biosphere by catalyzing biogeochemical processes, including carbon and nitrogen cycles. Anaerobic steroid catabolism by the denitrifying bacteria is relevant to both cycles. Although huge amounts of steroid compounds are produced and released to the environments by animals, fungi, and plants, to date almost nothing is known about how bacteria degrade steroid compounds in anoxic environments. Currently, we apply molecular and OMICs approaches to identify the intermediates, genes, and enzymes involved in anaerobic steroid catabolic pathways.
  • Allelochemicals produced by cyanobacteria: Bioactive compounds synthesized by freshwater and marine cyanobacteria have been studied in great details. However, much less is known about the bioactive secondary metabolites produced by terrestrial species. Metabolomic techniques are applied to search for antimicrobial compounds produced by cyanobateria inhabiting the surfaces of rock and bark, and soils.
Research Interests
  • Metabolic diversity of bacteria, especially anaerobes
  • Microbial metabolomics
  • Biodiversity of bacteria and algae
    Ongoing projects
    • Anaerobic metabolism of steroids by the denitrifying bacteria (NSC grant)
    • Aerobic metabolism of steroids by bacteria
    • Bioactive secondary metabolites produced by cyanobacteria
      Publications (2013-2017)
      1. Yi-Lung Chen, Chia-Hsiang Wang, Fu-Chun Yang, Wael Ismail, Po-Hsiang Wang, Chao-Jen Shih, Yu-Ching Wu, and Yin-Ru Chiang*, 2016, “Identification of Comamonas testosteroni as an androgen degrader in sewage.”, Scientific Reports, 6, 35386. (SCI) (IF: 5.228; SCI ranking: 11.1%)
      2. Fu-Chun Yang, Yi-Lung Chen, Sen-Lin Tang, Chang-Ping Yu, Po-Hsiang Wang, Wael Ismail, Chia-Hsiang Wang, Jiun-Yan Ding, Cheng-Yu Yang, Chia-Ying Yang, and Yin-Ru Chiang*, 2016, “Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment”, ISME Journal, 10, 1967-1983. (SCI) (IF: 9.328; SCI ranking: 2.7%,6.5%)
      3. Jiun-Yan Ding,Jia-Ho Shiu,Wen-Ming Chen, Yin-Ru Chiang, and Sen-Lin Tang, 2016, “Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33 with its coral host.”, Frontiers in Microbiology, 7, 251. (SCI) (IF: 4.165; SCI ranking: 18.7%)
      4. Lin, C. W., Wang, P. H., Ismail, W., Tsai Y. W., El Nayal, A., Yang, C. Y., Yang, F. C., Wang, C.-H., and *Chiang, Y. R., 2015, “Substrate uptake and subcellular compartmentation of anoxic cholesterol catabolism in Sterolibacterium denitrificans.”, JOURNAL OF BIOLOGICAL CHEMISTRY, 290, 1155-1169. (SCI) (IF: 4.258; SCI ranking: 24.6%)
      5. Wang, P. H., Yu, C. P., Lin, C. W., Ismail, W., Wey, S. P., Kuo, A. T., and *Chiang, Y. R., 2014, “Anoxic androgen degradation by denitrifying Sterolibacterium denitrificans via the 2,3-seco-pathway.”, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(11), 3442-3452. (SCI) (IF: 3.823; SCI ranking: 25.2%,20.5%)
      6. Chang, Y. C., Lu, C. K., Chiang, Y. R., Wang, G. J., Ju, Y. M., Kuo, Y. H., and *Lee, T. H., 2014, “Diterpene glycosides and polyketides from Xylotumulus gibbisporus.”, JOURNAL OF NATURAL PRODUCTS, 77, 751-757. (SCI) (IF: 3.662; SCI ranking: 22.4%,12%,13.6%)
      7. *Ismail, W., Alhamad, N. A., El-Sayed, W. S., El Nayal, A. M., Chiang, Y. R., and Hamzah, R. Y., 2013, “Bacterial degradation of the saturate fraction of Arabian light crude oil: biosurfactant production and the effect of ZnO nanoparticles.”, Journal of Petroleum and Environmental Biotechnology, 4, 163. (new Journal)
      8. Yin-Ru Chiang, Ann Li, Yann-Lii Leu, Jia-You Fang and Yin-Ku Lin*, 2013, “An in vitro Study of the Antimicrobial Effects of Indigo Naturalis Prepared from Strobilanthes formosanus Moore”, MOLECULES, 18(11), 14381-14396. (SCI) (IF: 2.465; SCI ranking: 40.7%)
      9. Wang, P. H., Lee, T. H., Ismail, W., Tsai, C. Y, Lin, C. W., Tsai, Y. W., and *Chiang, Y. R., 2013, “An oxygenase-independent cholesterol catabolic pathway operates under oxic conditions.”, PLoS One, 8(6), e66675. (SCI) (IF: 3.057; SCI ranking: 17.5%)
      10. Wang, P. H., Leu, Y. L., Ismail, W., Tang, S. L., Tsai, C. Y., Chen, H. J., Kao, A. T., and *Chiang, Y. R., 2013, “The anaerobic and aerobic cleavage of the steroid core ring structure by Steroidobacter denitrificans. ”, JOURNAL OF LIPID RESEARCH, 54, 1493-1504. (SCI) (IF: 4.368; SCI ranking: 23.2%)