Faculty list

Dr. Sen-Lin Tang

Research Fellow
Ph.D. University of Melbourne
Research Fields
Virology, Archaeal biology, Microbial genomics, and Computational biology
Major Research Achievements (2013-2017)
  • Microbes are known as one of the key members in coral holobionts and affect nutrient supply and health and disease of corals. To understand the roles of microbial community in coral holobionts, my colleagues and I have devoted on the studies of coral-associated bacteria since our joining Academia Sinica in 2007. As far as our best knowledge, we are the first team in Taiwan unveiled Stylophora pistillata-associated bacterial community (also coral-associated bacterial community) using culture independent molecular approach, which research results have been published in a renowned international journal, Applied and Environmental Microbiology (Hong et al., 2009) and elected as one of the most important achievements by the 2010-2011 Academia Sinica Review Report. In this study, we suggested that the effect of environment-specificity to coral-associated bacterial community is more significant than that of host species-specificity, and proposed a multifactor interaction model to illustrate this issue (i.e., which effects are more radical in driving the structure of bacterial community) and to emphasize such effect on specificity of coral-associated microbes is in fact an integrated, compound underlying impacts of environments, coral species, bacterial composition and temporal factors.
  • Furthermore, we worked intensively on a one-year monthly survey for dynamics of microbial communities in Isopora palifera using massively parallel pyrosequencing and which results have been accepted by a prestigious international journal, International Society for Microbial Ecology Journal (Chen, et al., 2010). We are the first team in the world employing the newly improved next generation sequencing technique and lately developed bioinformatics tool (i.e., Greedy-Fetching method, Tseng et al., BMC Bioinformatics in submission) to detect the dynamics of coral-associated microbial community and we have further applied the most comprehensive compositional analysis of coral-associated bacterial community from our monthly-coral samplings. The result of the study presents surprisingly a high biodiversity of coral-associated bacterial community and highly dynamic of two algal symbiont clades in Isopora palifera, which may change the traditional view to biodiversity of coral-associated bacteria and dynamics of algal symbionts in coral.
Research Interests
  • Microbial ecology and diversity
  • Microbial genomics (Metagenomics)
  • Computational biology
    Ongoing projects
    • Biodiversity of microbial communities in coral reefs and salt lakes
    • Microbial community genomics in South China Sea and Fei-tsui Water Reservoir
      Publications (2009-2017)
      1. Lee, S. T.M.*, S. K. Davy, S.-L. Tang*, P. S Kench, 2017, “Water flow buffers shifts in bacterial community structure in heat-stressed Acropora muricata”, SCIENTIFIC REPORTS, 7, 43600. (SCI) (IF: 5.228; SCI ranking: 11.1%)
      2. Fu-Chun Yang, Yi-Lung Chen, Sen-Lin Tang, Chang-Ping Yu, Po-Hsiang Wang, Wael Ismail, Chia-Hsiang Wang, Jiun-Yan Ding, Cheng-Yu Yang, Chia-Ying Yang, and Yin-Ru Chiang*, 2016, “Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment”, ISME Journal, 10(8), 1967-1983. (SCI) (IF: 9.328; SCI ranking: 2.7%,6.5%)
      3. Shih-Yi Sheu, Li-Ping Liu, Sen-Lin Tang, and Wen-Ming Chen, 2016, “Thalassotalea euphylliae sp. nov., isolated from the torch coral Euphyllia glabrescens”, International Journal of Systematic and Evolutionary Microbiology, 66, 5039-5045. (SCI) (IF: 2.439; SCI ranking: 52.8%)
      4. Shan-Hua Yang , Pei-Wen Chiang , Tin-Chang Hsu , Shuh-Ji Kao , Sen-Lin Tang*, 2016, “Bacterial Community Associated with Organs of Shallow Hydrothermal Vent Crab Xenograpsus testudinatus near Kuishan Island, Taiwan”, PLoS One, 11(3), e0150597. (SCI) (IF: 3.057; SCI ranking: 17.5%)
      5. Jeng-Wei Tsai,* Timothy K. Kratz, James A. Rusak, Wan-Yu Shih, Wen-Cheng Liu, Sen-Lin Tang, and Chih-Yu Chiu, 2016, “Absence of winter and spring monsoon changes water level and rapidly shifts metabolism in a subtropical lake”, Inland Waters, 6(3), 436-448. (SCI) (IF: 1.776; SCI ranking: 43.3%,40%)
      6. Bayanmunkh Baatar, Pei-Wen Chiang, Denis Yu Rogozin, Yu-Ting Wu, Ching-Hung Tseng, Cheng-Yu Yang, Hsiu-Hui Chiu, Bolormaa Oyuntsetseg, Andrey G. Degermendzhy and Sen-Lin Tang*, 2016, “Bacterial Communities of Three Saline Meromictic Lakes in Central Asia”, PLOS ONE, 11(3), e0150847. (SCI) (IF: 3.057; SCI ranking: 17.5%)
      7. Lan-Feng Fan, Hsing-Ju Chen, Hwey-Lian Hsieh, Hsing-Juh Lin, Sen-Lin Tang*, 2016, “Comparing abundance, composition and environmental influences on prokaryotic ammonia oxidizers in two subtropical constructed wetlands”, ECOLOGICAL ENGINEERING, 90, 336-346. (SCI) (IF: 2.74; SCI ranking: 34%,33.3%,29.3%)
      8. Ching-Hung Tseng, Jaw-Town Lin, Hsiu-Jon Ho, Zi-Lun Lai, Chang-Bi Wang, Sen-Lin Tang*, and Chun-Ying Wu*, 2016, “Gastric microbiota and predicted gene functions are altered after subtotal gastrectomy in patients with gastric cancer”, Scientific Reports, 6, 20701. (SCI) (IF: 5.228; SCI ranking: 11.1%)
      9. Jiun-Yan Ding,Jia-Ho Shiu,Wen-Ming Chen,Yin-Ru Chiang,Sen-Lin Tang*, 2016, “Genomic insight into the host-endosymbiont relationship of Endozoicomonas montiporae CL-33 with its coral host”, FRONTIERS IN MICROBIOLOGY, 7, 251. (SCI) (IF: 4.165; SCI ranking: 18.7%)
      10. Sonny T.M. Lee*,Simon K. Davy,Sen-Lin Tang*,Paul S Kench,, 2016, “Mucus sugar content shapes the bacterial community structure in thermally stressed Acropora muricata”, Frontiers in Microbiology, 7, 371. (SCI) (IF: 4.165; SCI ranking: 18.7%)
      11. Yang, Shan-Hua; Lee, Sonny; Huang, Chang-Rung; Tseng, Ching-Hung; Chiang, Pei-Wen; Chen, Chung-Pin; Chen, Hsing-Ju; Tang, Sen-Lin*, 2016, “Prevalence of potential nitrogen-fixing, green sulphur bacteria in the skeleton of reef-building coral Isopora palifera”, LIMNOLOGY AND OCEANOGRAPHY, 61(3), 1078-1086. (SCI) (IF: 3.66; SCI ranking: 6.6%,10%)
      12. Kuei-Han Lin, Ben-Yang Liao, Hao-Wei Chang, Shiao-Wei Huang, Ting-Yan Chang, Cheng-Yu Yang, Yu-Bin Wang, Yu-Teh Kirk Lin, Yu-Wei Wu, Sen-Lin Tang*, Hon-Tsen Yu*, 2015, “Metabolic characteristics of dominant microbes and key rare species from an acidic hot spring in Taiwan revealed by metagenomics”, BMC GENOMICS, 16(1), 1029. (SCI) (IF: 3.867; SCI ranking: 25.9%,19.9%)
      13. Sonny Lee, Simon Davy, Sen-Lin Tang*, Tung-Yung Fan, Paul Kench, 2015, “Successive shifts in the microbial community of the surface mucus layer and tissues of the coral Acropora muricata under thermal stress”, FEMS MICROBIOLOGY ECOLOGY, 91(12), fiv142. (SCI) (IF: 3.53; SCI ranking: 30.1%)
      14. Chia-Jung Hsieh, Shing Hei Zhan, Yiching Lin, Sen-Lin Tang and Shao-Lun Liu*, 2015, “Analysis of rbcL sequences reveals the global biodiversity, community structure, and biogeographical pattern of thermoacidophilic red algae (Cyanidiales)”, JOURNAL OF PHYCOLOGY, 51(4), 682-694. (SCI) (IF: 2.536; SCI ranking: 22.5%,15.4%)
      15. Yu-Te Lin, William B. Whitman, David C. Coleman, Shiang-Yun Shi, Sen-Lin Tang, Chih-Yu Chiu*, 2015, “Changes of soil bacterial communities in bamboo plantations at different elevations”, FEMS MICROBIOLOGY ECOLOGY, 91(5), fiv033. (SCI) (IF: 3.53; SCI ranking: 30.1%)
      16. Ching-Hung Tseng, Pei-Wen Chiang, Hung-Chun Lai, Fuh-Kwo Shiah, Ting-Chang Hsu, Yi-Lung Chen, Liang-Saw Wen, Chun-Mao Tseng, Wung-Yang Shieh, Isaam Saeed, Saman Halgamuge, Sen-Lin Tang*, 2015, “Prokaryotic assemblages and metagenomes in pelagic zones of the South China Sea”, BMC GENOMICS, 16, 219. (SCI) (IF: 3.867; SCI ranking: 25.9%,19.9%)
      17. Duleepa Jayasundara, I. Saeed, B.C. Chang, S.-L. Tang and S.K. Halgamuge*, 2015, “Accurate reconstruction of viral quasispecies spectra through improved estimation of strain richness”, BMC BIOINFORMATICS, 16(Suppl 18), S3. (SCI) (IF: 2.435; SCI ranking: 39.8%,50.6%,17.9%)
      18. Hsiu-Hui Chiu, Denis Yu. Rogozin, Ssu-Po Huang, Andrei G. Degermendzhy, Wung Yang Shieh, and Sen-Lin Tang*, 2014, “ Aliidiomarina shirensis sp. nov., a halophilic bacterium isolated from Shira Lake in Khakasia, southern Siberia, and a proposal to transfer Idiomarina maris to the genus Aliidiomarina”, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 64, 1334-1339. (SCI) (IF: 2.439; SCI ranking: 52.8%)
      19. Lin, Y.T., Tang, S.L., Pai, C.W., Whitman, W.B., David C. Coleman, D.C., and Chiu, C.Y.*, 2014, “Changes in the soil bacterial communities in a cedar plantation invaded by moso bamboo”, MICROBIAL ECOLOGY, 67(2), 421-429. (SCI) (IF: 3.232; SCI ranking: 3.8%,35%,24.7%)
      20. Jiun-Yan Ding, Pei-Wen Chiang, Mei-Jhu Hong, Mike Dyall-Smith, Sen-Lin Tang*, 2014, “Complete Genome Sequence of the Extremely Halophilic Archaeon Haloarcula hispanica Strain N601”, Genome Announcement, no. 2 e00178-14. (Others)
      21. Ching-Hung Tseng and Sen-Lin Tang*,, 2014, “Marine Microbial Metagenomics: From Individual to the Environment”, Int. J. Mol. Sci., 15, 8878-8892. (SCI) (IF: 3.257; SCI ranking: 38.1%,31.9%)
      22. Silk Yu Lin, Wung Yang Shieh, Jwo-Sheng Chen, Sen-Lin Tang*, 2013, “Complete Genome Sequence of Simiduia agarivorans SA1T, a Marine Bacterium Able To Degrade a Variety of Polysaccharides ”, Genome Announcements, 1(1), e00039-12. (new journal)
      23. Ching-Hung Tseng, Pei-Wen Chiang, Fuh-Kwo Shiah, Yi-Lung Chen, Jia-Rong Liou, Ting-Chang Hsu, Suhinthan Maheswararajah, Isaam Saeed, Saman Halgamuge, Sen-Lin Tang*, 2013, “Microbial and viral metagenomes of a subtropical freshwater reservoir subject to climatic disturbances”, ISME Journal, 7, 2374-2386. (SCI) (IF: 9.328; SCI ranking: 2.7%,6.5%)
      24. Kate Porter, Sen-Lin Tang, Chung-Pin Chen, Pei-Wen Chiang, Mei-Jhu Hong and Mike L. Dyall Smith, 2013, “PH1, an archaeovirus of Haloarcula hispanica related to SH1 and HHIV-2”, Archaea, 456318. (SCI) (IF: 3.234; SCI ranking: 34.1%)
      25. Wang, P. H., Leu, Y. L., Ismail, W., Tang, S. L., Tsai, C. Y., Chen, H. J., Kao, A. T., and *Chiang, Y. R., 2013, “The anaerobic and aerobic cleavage of the steroid core ring structure by Steroidobacter denitrificans”, JOURNAL OF LIPID RESEARCH, 54(5), 1493-1504. (SCI) (IF: 4.368; SCI ranking: 23.2%)
      26. I. Saeed*, S-L. Tang*, S.K. Halgamuge, 2012, “Unsupervised discovery of microbial population structure within metagenomes using nucleotide base composition”, NUCLEIC ACIDS RESEARCH, 40(5), e34. (SCI) (IF: 9.202; SCI ranking: 6.2%)
      27. Lan-Feng Fan, Sen-Lin Tang*, Chang-Po Chen, Hwey-Lian Hsieh*, 2012, “Diversity and Composition of Sulfate- and Sulfite-Reducing Prokaryotes as Affected by Marine-Freshwater Gradient and Sulfate Availability,”, MICROBIAL ECOLOGY, 63(1), 224-237. (SCI) (IF: 3.232; SCI ranking: 3.8%,35%,24.7%)
      28. Hsiu-Hui Chiu, Andreas Mette, Jia-Ho Hsu, and Sen-Lin Tang*, 2012, “Bacterial Distribution in the Epidermis and Mucus of the Coral Euphyllia glabrescens by CARD-FISH”, ZOOLOGICAL STUDIES, 51(8), 1332-1342. (SCI) (IF: 0.885; SCI ranking: 56.5%)
      29. Cheng, T.-W. , Y.-H. Chang, S.-L. Tang, C.-H. Tseng, P.-W. Chiang, K.-T. Chang, C.-H. Sun, Y.-G. Chen, H.-C. Kuo, C.-H. Wang, P.-H. Chu, S.-R. Song, P.-L. Wang, and L.-H. Lin,, 2012, “Metabolic stratification driven by surface and subsurface interactions in a terrestrial mud volcano”, ISME Journal, 6(12), 2280-2290. (SCI) (IF: 9.328; SCI ranking: 2.7%,6.5%)
      30. Saeed, Isaam*, Sen-Lin Tang*, and Saman Halgamuge, 2011, “Unsupervised discovery of microbial population structure within metagenomes using nucleotide base composition”, NUCLEIC ACIDS RESEARCH, 40(5), e34. (SCI) (IF: 9.202; SCI ranking: 6.2%)
      31. Sen-Lin Tang*, Mei-Jhu Hong, Ming-Hui Liao, Wann-Neng Jane, Pei-Wen Chiang, Chung-Bin Chen, and Chaolun Allen Chen, 2011, “Bacteria associated with an encrusting sponge (Terpios hoshinota) and the corals partially covered by the sponge”, ENVIRONMENTAL MICROBIOLOGY, 13(5), 1179-1191. (SCI) (IF: 5.932; SCI ranking: 13%)
      32. Shurong Zheng, Richard A. Johnson, Yi-Feng Chang, Kunio Shimizu, Chia-Chang Wang, and Sen-Lin Tang, Grace S. Shieh*, 2011, “Modeling And Comparing the Organization of Circular Genomes”, BIOINFORMATICS, 27(7), 912-918. (SCI) (IF: 5.766; SCI ranking: 9.1%,5.4%,9.3%)
      33. J.-T. Wang, P.-J Meng, E. Sampayo, S.-L. Tang, C. A. Chen, 2011, “Photosystem II breakdown induced by reactive oxygen species (ROS) in the freshly-isolated Symbiodinium of Montipora (Scleractinia; Acropordiae)”, Marine Ecology Progress Series, 422, 51-62. (SCI) (IF: 2.361; SCI ranking: 24.6%,38%,22.1%)
      34. Chung-Pin Chen, Ching-Hung Tseng, Chaolun Allen Chen, Sen-Lin Tang*, 2010, “The dynamics of microbial parternships in the coral Isopora palifera”, ISME Journal, 5(4), 728-740. (SCI) (IF: 9.328; SCI ranking: 2.7%,6.5%)
      35. Sen-Lin Tang*, Bill CH Chang and Saman K Halgamuge, 2010, “Gene functionality’s influence on the second codon: a large-scale survey of second codon composition in three domains”, Genomics, 96(2), 92-101. (SCI) (IF: 2.386; SCI ranking: 41.6%,53.6%)
      36. Lin YT, Huang YJ, Tang SL, Whitman WB, Coleman DC, Chiu CY, 2010, “Bacterial Community Diversity in Undisturbed Perhumid Montane Forest Soils in Taiwan”, Microbial Ecology, 59(2), 369-378. (SCI) (IF: 3.232; SCI ranking: 3.8%,35%,24.7%)
      37. Mei-Jhu Hong, Yi-Ting Yu, Chao-Lun A. Chen, Pei-Wen Chiang, Sen-Lin Tang*, 2009, “Influence of species specificity and other factors on bacteria associated with Stylophora pistillata in Taiwan. Applied and Environmental Microbiology”, Applied and Environmental Microbiology, 75:7796-7806. (SCI) (IF: 3.823; SCI ranking: 25.2%,20.5%)